PDF DatasheetHuman mRNA-decapping enzyme 1A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant mRNA-decapping enzyme 1A based upon sequence from: Human
Host: QP8201 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) mRNA-decapping enzyme 1A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8201.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu582
Amino Acid Sequence: MEALSRAGQE MSLAALKQHD PYITSIADLT GQVALYTFCP KANQWEKTDI EGTLFVYRRS ASPYHGFTIV NRLNMHNLVE PVNKDLEFQL HEPFLLYRNA SLSIYSIWFY DKNDCHRIAK LMADVVEEET RRSQQAARDK QSPSQANGCS DHRPIDILEM LSRAKDEYER NQMGDSNISS PGLQPSTQLS NLGSTETLEE MPSGSQDKSA PSGHKHLTVE ELFGTSLPKE QPAVVGLDSE EMERLPGDAS QKEPNSFLPF PFEQLGGAPQ SETLGVPSAA HHSVQPEITT PVLITPASIT QSNEKHAPTY TIPLSPVLSP TLPAEAPTAQ VPPSLPRNST MMQAVKTTPR QRSPLLNQPV PELSHASLIA NQSPFRAPLN VTNTAGTSLP SVDLLQKLRL TPQHDQIQTQ PLGKGAMVAS FSPAAGQLAT PESFIEPPSK TAAARVAASA SLSNMVLAPL QSMQQNQDPE VFVQPKVLSS AIQVAGAPLV TATTTAVSSV LLAPSVFQQT VTRSSDLERK ASSPSPLTIG TPESQRKPSI ILSKSQLQDT LIHLIKNDSS FLSTLHEVYL QVLTKNKDNH NL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human mRNA-decapping enzyme 1A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human mRNA-decapping enzyme 1A Protein General Information | |
|---|---|
| Alternate Names | |
| SMAD4IP1; HSA275986; Nbla00360; SMIF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DCP1A |
| Entrez Gene ID | 55802 |
| Ensemble Gene ID | ENSG00000272886 |
| RefSeq Protein Accession(s) | NP_001277133.1 |
| RefSeq mRNA Accession(s) | NM_001290204.1, NM_001290205.1, NM_001290206.1, NM_001290207.1, NM_018403.6 |
| UniProt ID(s) | Q9NPI6 |
| UniGene ID(s) | Hs.476353 |
| HGNC ID(s) | HGNC:18714 |
| COSMIC ID Link(s) | DCP1A |
| KEGG Gene ID(s) | hsa:55802 |
| PharmGKB ID(s) | PA134931379 |
| General Description of Recombinant Human mRNA-decapping enzyme 1A Protein. | |
| Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5′-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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