PDF DatasheetHuman Glutaminase liver isoform, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Glutaminase liver isoform, mitochondrial based upon sequence from: Human
Host: QP8210 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Glutaminase liver isoform, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8210.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly15 – Val602
Amino Acid Sequence: GSHCGRGGWG HPSRSPLLGG GVRHHLSEAA AQGRETPHSH QPQHQDHDSS ESGMLSRLGD LLFYTIAEGQ ERIPIHKFTT ALKATGLQTS DPRLRDCMSE MHRVVQESSS GGLLDRDLFR KCVSSNIVLL TQAFRKKFVI PDFEEFTGHV DRIFEDVKEL TGGKVAAYIP QLAKSNPDLW GVSLCTVDGQ RHSVGHTKIP FCLQSCVKPL TYAISISTLG TDYVHKFVGK EPSGLRYNKL SLNEEGIPHN PMVNAGAIVV SSLIKMDCNK AEKFDFVLQY LNKMAGNEYM GFSNATFQSE KETGDRNYAI GYYLKEKKCF PKGVDMMAAL DLYFQLCSVE VTCESGSVMA ATLANGGICP ITGESVLSAE AVRNTLSLMH SCGMYDFSGQ FAFHVGLPAK SAVSGAILLV VPNVMGMMCL SPPLDKLGNS HRGTSFCQKL VSLFNFHNYD NLRHCARKLD PRREGAEIRN KTVVNLLFAA YSGDVSALRR FALSAMDMEQ KDYDSRTALH VAAAEGHIEV VKFLIEACKV NPFAKDRWGN IPLDDAVQFN HLEVVKLLQD YQDSYTLSET QAEAAAEALS KENLESMV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Glutaminase liver isoform, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Glutaminase liver isoform, mitochondrial Protein General Information | |
|---|---|
| Alternate Names | |
| hLGA; GA; GLS; LGA | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GLS2 |
| Entrez Gene ID | 27165 |
| Ensemble Gene ID | ENSG00000135423 |
| RefSeq Protein Accession(s) | NP_001267727.1 |
| RefSeq mRNA Accession(s) | NM_001280798.1, NM_013267.3 |
| UniProt ID(s) | Q9UI32 |
| UniGene ID(s) | Hs.212606 |
| HGNC ID(s) | HGNC:29570 |
| COSMIC ID Link(s) | GLS2 |
| KEGG Gene ID(s) | hsa:27165 |
| PharmGKB ID(s) | PA134933506 |
| General Description of Recombinant Human Glutaminase liver isoform, mitochondrial Protein. | |
| Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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