PDF DatasheetHuman ADP-ribosylation factor-like protein 6 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant ADP-ribosylation factor-like protein 6 based upon sequence from: Human
Host: QP8213 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ADP-ribosylation factor-like protein 6, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8213.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly1 – Thr186aa
Amino Acid Sequence: GLLDRLSVLL GLKKKEVHVL CLGLDNSGKT TIINKLKPSN AQSQNILPTI GFSIEKFKSS SLSFTVFDMS GQGRYRNLWE HYYKEGQAII FVIDSSDRLR MVVAKEELDT LLNHPDIKHR RIPILFFANK MDLRDAVTSV KVSQLLCLEN IKDKPWHICA SDAIKGEGLQ EGVDWLQDQI QTVKT
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human ADP-ribosylation factor-like protein 6 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human ADP-ribosylation factor-like protein 6 Protein General Information | |
|---|---|
| Alternate Names | |
| BBS3; RP55 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ARL6 |
| Entrez Gene ID | 84100 |
| Ensemble Gene ID | ENSG00000113966 |
| RefSeq Protein Accession(s) | NP_001265222.1 |
| RefSeq mRNA Accession(s) | NM_001278293.2, NM_001323513.1, NM_032146.5, NM_177976.3, XM_017007311.1 |
| UniProt ID(s) | Q9H0F7 |
| UniGene ID(s) | Hs.373801 |
| HGNC ID(s) | HGNC:13210 |
| COSMIC ID Link(s) | ARL6 |
| KEGG Gene ID(s) | hsa:84100 |
| PharmGKB ID(s) | PA134931939 |
| General Description of Recombinant Human ADP-ribosylation factor-like protein 6 Protein. | |
| Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia. Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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