PDF DatasheetHuman Notchless protein homolog 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Notchless protein homolog 1 based upon sequence from: Human
Host: QP8226 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Notchless protein homolog 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8226.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Arg485
Amino Acid Sequence: AAAVPDEAVA RDVQRLLVQF QDEGGQLLGS PFDVPVDITP DRLQLVCNAL LAQEDPLPLA FFVHDAEIVS SLGKTLESQA VETEKVLDII YQPQAIFRVR AVTRCTSSLE GHSEAVISVA FSPTGKYLAS GSGDTTVRFW DLSTETPHFT CKGHRHWVLS ISWSPDGRKL ASGCKNGQIL LWDPSTGKQV GRTLAGHSKW ITGLSWEPLH ANPECRYVAS SSKDGSVRIW DTTAGRCERI LTGHTQSVTC LRWGGDGLLY SASQDRTIKV WRAHDGVLCR TLQGHGHWVN TMALSTDYAL RTGAFEPAEA SVNPQDLQGS LQELKERALS RYNLVRGQGP ERLVSGSDDF TLFLWSPAED KKPLTRMTGH QALINQVLFS PDSRIVASAS FDKSIKLWDG RTGKYLASLR GHVAAVYQIA WSADSRLLVS GSSDSTLKVW DVKAQKLAMD LPGHADEVYA VDWSPDGQRV ASGGKDKCLR IWRR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Notchless protein homolog 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Notchless protein homolog 1 Protein General Information | |
|---|---|
| Alternate Names | |
| Nle | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NLE1 |
| Entrez Gene ID | 54475 |
| Ensemble Gene ID | ENSG00000073536 |
| RefSeq Protein Accession(s) | NP_001014445.1 |
| RefSeq mRNA Accession(s) | NM_001014445.2, NM_018096.4, XM_017024777.1 |
| UniProt ID(s) | Q9NVX2 |
| UniGene ID(s) | Hs.85570 |
| HGNC ID(s) | HGNC:19889 |
| COSMIC ID Link(s) | NLE1 |
| KEGG Gene ID(s) | hsa:54475 |
| PharmGKB ID(s) | PA142671263 |
| General Description of Recombinant Human Notchless protein homolog 1 Protein. | |
| Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several mbers of the Wnt pathway, probably via its effects on Notch activity. Required during bryogenesis for inner mass cell survival . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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