PDF DatasheetHuman Cell division cycle protein 23 homolog Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Cell division cycle protein 23 homolog based upon sequence from: Human
Host: QP8237 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cell division cycle protein 23 homolog, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8237.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala14 – Asn591
Amino Acid Sequence: AAVAPVLSIN SDFSDLREIK KQLLLIAGLT RERGLLHSSK WSAELAFSLP ALPLAELQPP PPITEEDAQD MDAYTLAKAY FDVKEYDRAA HFLHGCNSKK AYFLYMYSRY LSGEKKKDDE TVDSLGPLEK GQVKNEALRE LRVELSKKHQ ARELDGFGLY LYGVVLRKLD LVKEAIDVFV EATHVLPLHW GAWLELCNLI TDKEMLKFLS LPDTWMKEFF LAHIYTELQL IEEALQKYQN LIDVGFSKSS YIVSQIAVAY HNIRDIDKAL SIFNELRKQD PYRIENMDTF SNLLYVRSMK SELSYLAHNL CEIDKYRVET CCVIGNYYSL RSQHEKAALY FQRALKLNPR YLGAWTLMGH EYMEMKNTSA AIQAYRHAIE VNKRDYRAWY GLGQTYEILK MPFYCLYYYR RAHQLRPNDS RMLVALGECY EKLNQLVEAK KCYWRAYAVG DVEKMALVKL AKLHEQLTES EQAAQCYIKY IQDIYSCGEI VEHLEESTAF RYLAQYYFKC KLWDEASTCA QKCCAFNDTR EEGKALLRQI LQLRNQGETP TTEVPAPFFL PASLSANNTP TRRVSPLN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Cell division cycle protein 23 homolog Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Cell division cycle protein 23 homolog Protein General Information | |
|---|---|
| Alternate Names | |
| APC8; CUT23; ANAPC8 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CDC23 |
| Entrez Gene ID | 8697 |
| Ensemble Gene ID | ENSG00000094880 |
| RefSeq Protein Accession(s) | NP_004652.2 |
| RefSeq mRNA Accession(s) | NM_004661.3 |
| UniProt ID(s) | Q9UJX2 |
| UniGene ID(s) | Hs.73625 |
| HGNC ID(s) | HGNC:1724 |
| COSMIC ID Link(s) | CDC23 |
| KEGG Gene ID(s) | hsa:8697 |
| PharmGKB ID(s) | PA26258 |
| General Description of Recombinant Human Cell division cycle protein 23 homolog Protein. | |
| Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of ‘Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ‘Lys-48’- and ‘Lys-63’-linked polyubiquitin chains. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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