PDF DatasheetHuman Long-chain-fatty-acid–CoA ligase 5 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Long-chain-fatty-acid–CoA ligase 5 based upon sequence from: Human
Host: QP8244 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Long-chain-fatty-acid–CoA ligase 5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8244.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Thr33 – Asp683
Amino Acid Sequence: TRPQPVLPLL DLNNQSVGIE GGARKGVSQK NNDLTSCCFS DAKTMYEVFQ RGLAVSDNGP CLGYRKPNQP YRWLSYKQVS DRAEYLGSCL LHKGYKSSPD QFVGIFAQNR PEWIISELAC YTYSMVAVPL YDTLGPEAIV HIVNKADIAM VICDTPQKAL VLIGNVEKGF TPSLKVIILM DPFDDDLKQR GEKSGIEILS LYDAENLGKE HFRKPVPPSP EDLSVICFTS GTTGDPKGAM ITHQNIVSNA AAFLKCVEHA YEPTPDDVAI SYLPLAHMFE RIVQAVVYSC GARVGFFQGD IRLLADDMKT LKPTLFPAVP RLLNRIYDKV QNEAKTPLKK FLLKLAVSSK FKELQKGIIR HDSFWDKLIF AKIQDSLGGR VRVIVTGAAP MSTSVMTFFR AAMGCQVYEA YGQTECTGGC TFTLPGDWTS GHVGVPLACN YVKLEDVADM NYFTVNNEGE VCIKGTNVFK GYLKDPEKTQ EALDSDGWLH TGDIGRWLPN GTLKIIDRKK NIFKLAQGEY IAPEKIENIY NRSQPVLQIF VHGESLRSSL VGVVVPDTDV LPSFAAKLGV KGSFEELCQN QVVREAILED LQKIGKESGL KTFEQVKAIF LHPEPFSIEN GLLTPTLKAK RGELSKYFRT QIDSLYEHIQ D
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Long-chain-fatty-acid–CoA ligase 5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Long-chain-fatty-acid–CoA ligase 5 Protein General Information | |
|---|---|
| Alternate Names | |
| ACS5; ACS2; FACL5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ACSL5 |
| Entrez Gene ID | 51703 |
| Ensemble Gene ID | ENSG00000197142 |
| RefSeq Protein Accession(s) | NP_057318.2 |
| RefSeq mRNA Accession(s) | NM_016234.3, NM_203379.1, NM_203380.1 |
| UniProt ID(s) | Q9ULC5 |
| UniGene ID(s) | Hs.11638 |
| HGNC ID(s) | HGNC:16526 |
| COSMIC ID Link(s) | ACSL5 |
| KEGG Gene ID(s) | hsa:51703 |
| PharmGKB ID(s) | PA27969 |
| General Description of Recombinant Human Long-chain-fatty-acid–CoA ligase 5 Protein. | |
| Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.