PDF DatasheetHuman Protein MEMO1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Protein MEMO1 based upon sequence from: Human
Host: QP8268 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Protein MEMO1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8268.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – His297
Amino Acid Sequence: MSNRVVCREA SHAGSWYTAS GPQLNAQLEG WLSQVQSTKR PARAIIAPHA GYTYCGSCAA HAYKQVDPSI TRRIFILGPS HHVPLSRCAL SSVDIYRTPL YDLRIDQKIY GELWKTGMFE RMSLQTDEDE HSIEMHLPYT AKAMESHKDE FTIIPVLVGA LSESKEQEFG KLFSKYLADP SNLFVVSSDF CHWGQRFRYS YYDESQGEIY RSIEHLDKMG MSIIEQLDPV SFSNYLKKYH NTICGRHPIG VLLNAITELQ KNGMNMSFSF LNYAQSSQCR NWQDSSVSYA AGALTVH
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Protein MEMO1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Protein MEMO1 Protein General Information | |
|---|---|
| Alternate Names | |
| CGI-27; C2orf4; MEMO; NS5ATP7 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MEMO1 |
| Entrez Gene ID | 51072 |
| Ensemble Gene ID | ENSG00000162959 |
| RefSeq Protein Accession(s) | NP_001131074.1 |
| RefSeq mRNA Accession(s) | NM_001137602.2, NM_001301833.1, NM_001301852.1, NM_015955.3, XM_011532892.2, XM_017004255.1 |
| UniProt ID(s) | Q9Y316 |
| UniGene ID(s) | Hs.444969 |
| HGNC ID(s) | HGNC:14014 |
| COSMIC ID Link(s) | MEMO1 |
| KEGG Gene ID(s) | hsa:51072 |
| PharmGKB ID(s) | PA162395745 |
| General Description of Recombinant Human Protein MEMO1 Protein. | |
| May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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