PDF DatasheetHuman TIMM10B Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TIMM10B based upon sequence from: Human
Host: QP8270 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TIMM10B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8270.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser103
Amino Acid Sequence: MERQQQQQQQ LRNLRDFLLV YNRMTELCFQ RCVPSLHHRA LDAEEEACLH SCAGKLIHSN HRLMAAYVQL MPALVQRRIA DYEAASAVPG VAAEQPGVSP SGS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TIMM10B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TIMM10B Protein General Information | |
|---|---|
| Alternate Names | |
| TIM10B; FXC1; Tim9b; Mitochondrial import inner membrane translocase subunit Tim10 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TIMM10B |
| Entrez Gene ID | 26515 |
| Ensemble Gene ID | ENSG00000132286 |
| RefSeq Protein Accession(s) | NP_036324.1 |
| RefSeq mRNA Accession(s) | NM_012192.3 |
| UniProt ID(s) | Q9Y5J6 |
| UniGene ID(s) | Hs.54943 |
| HGNC ID(s) | HGNC:4022 |
| KEGG Gene ID(s) | hsa:26515 |
| PharmGKB ID(s) | PA28438 |
| General Description of Recombinant Human TIMM10B Protein. | |
| Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmbrane proteins into the mitochondrial inner mbrane. The TIM22 complex forms a twin-pore translocase that uses the mbrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermbrane space. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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