PDF DatasheetHuman USH1C Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant USH1C based upon sequence from: Human
Isoform: Isoform 4
Host: QP8285 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) USH1C, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8285.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 4
Expression Region: Met1 – Phe533
Amino Acid Sequence: MDRKVAREFR HKVDFLIEND AEKDYLYDVL RMYHQTMDVA VLVGDLKLVI NEPSRLPLFD AIRPLIPLKH QVEYDQLTPR RSRKLKEVRL DRLHPEGLGL SVRGGLEFGC GLFISHLIKG GQADSVGLQV GDEIVRINGY SISSCTHEEV INLIRTKKTV SIKVRHIGLI PVKSSPDEPL TWQYVDQFVS ESGGVRGSLG SPGNRENKEK KVFISLVGSR GLGCSISSGP IQKPGIFISH VKPGSLSAEV GLEIGDQIVE VNGVDFSNLD HKEGRELFMT DRERLAEARQ RELQRQELLM QKRLAMESNK ILQEQQEMER QRRKEIAQKA AEENERYRKE MEQIVEEEEK FKKQWEEDWG SKEQLLLPKT ITAEVHPVPL RKPKYDQGVE PELEPADDLD GGTEEQGEQD FRKYEEGFDP YSMFTPEQIM GKDVRLLRIK KEGSLDLALE GGVDSPIGKV VVSAVYERGA AERHGGIVKG DEIMAINGKI VTDYTLAEAE AALQKAWNQG GDWIDLVVAV CPPKEYDDEL TFF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human USH1C Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human USH1C Protein General Information | |
|---|---|
| Alternate Names | |
| USH1C; PDZ-73/NY-CO-38; PDZD7C; ush1cpst; AIE-75; DFNB18; DFNB18A; NY-CO-38; PDZ-45; PDZ-73; PDZ73; NY-CO-37 | |
| Molecular Weight | |
| Isoform 4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | USH1C |
| Entrez Gene ID | 10083 |
| Ensemble Gene ID | ENSG00000006611 |
| RefSeq Protein Accession(s) | NP_001284693.1 |
| RefSeq mRNA Accession(s) | NM_001297764.1, NM_005709.3, NM_153676.3 |
| UniProt ID(s) | Q9Y6N9 |
| UniGene ID(s) | Hs.502072 |
| HGNC ID(s) | HGNC:12597 |
| COSMIC ID Link(s) | USH1C |
| KEGG Gene ID(s) | hsa:10083 |
| PharmGKB ID(s) | PA37226 |
| General Description of Recombinant Human USH1C Protein. | |
| Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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