PDF DatasheetHuman Protein chibby homolog 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Protein chibby homolog 1 based upon sequence from: Human
Host: QP8286 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Protein chibby homolog 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8286.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys126
Amino Acid Sequence: MPFFGNTFSP KKTPPRKSAS LSNLHSLDRS TREVELGLEY GSPTMNLAGQ SLKFENGQWI AETGVSGGVD RREVQRLRRR NQQLEEENNL LRLKVDILLD MLSESTAESH LMEKELDELR ISRKRK
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Protein chibby homolog 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Protein chibby homolog 1 Protein General Information | |
|---|---|
| Alternate Names | |
| PGEA1; C22orf2; HS508I15A; arb1; PIGEA14; CBY; PIGEA-14 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CBY1 |
| Entrez Gene ID | 25776 |
| Ensemble Gene ID | ENSG00000100211 |
| RefSeq Protein Accession(s) | NP_001002880.2 |
| RefSeq mRNA Accession(s) | NM_001002880.1, NM_015373.3 |
| UniProt ID(s) | Q9Y3M2 |
| UniGene ID(s) | Hs.334911 |
| HGNC ID(s) | HGNC:1307 |
| COSMIC ID Link(s) | CBY1 |
| KEGG Gene ID(s) | hsa:25776 |
| PharmGKB ID(s) | PA25886 |
| General Description of Recombinant Human Protein chibby homolog 1 Protein. | |
| Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.