PDF DatasheetHuman Ras-related protein Rab-1A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ras-related protein Rab-1A based upon sequence from: Human
Host: QP8316 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ras-related protein Rab-1A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8316.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser2 – Cys205
Amino Acid Sequence: SSMNPEYDYL FKLLLIGDSG VGKSCLLLRF ADDTYTESYI STIGVDFKIR TIELDGKTIK LQIWDTAGQE RFRTITSSYY RGAHGIIVVY DVTDQESFNN VKQWLQEIDR YASENVNKLL VGNKCDLTTK KVVDYTTAKE FADSLGIPFL ETSAKNATNV EQSFMTMAAE IKKRMGPGAT AGGAEKSNVK IQSTPVKQSG GGCC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Ras-related protein Rab-1A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Ras-related protein Rab-1A Protein General Information | |
|---|---|
| Alternate Names | |
| RAB1; YPT1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RAB1A |
| Entrez Gene ID | 5861 |
| Ensemble Gene ID | ENSG00000138069 |
| RefSeq Protein Accession(s) | NP_004152.1 |
| RefSeq mRNA Accession(s) | NM_004161.4, NM_015543.1 |
| UniProt ID(s) | P62820 |
| UniGene ID(s) | Hs.310645 |
| HGNC ID(s) | HGNC:9758 |
| COSMIC ID Link(s) | RAB1A |
| KEGG Gene ID(s) | hsa:5861 |
| PharmGKB ID(s) | PA34107 |
| General Description of Recombinant Human Ras-related protein Rab-1A Protein. | |
| The small GTPases Rab are key regulators of intracellular mbrane trafficking, from the formation of transport vesicles to their fusion with mbranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to mbranes different sets of downstream effectors directly responsible for vesicle formation, movent, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell mbrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assbly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.