PDF DatasheetHuman Eukaryotic initiation factor 4A-II Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Eukaryotic initiation factor 4A-II based upon sequence from: Human
Host: QP8318 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Eukaryotic initiation factor 4A-II, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8318.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ile407
Amino Acid Sequence: MSGGSADYNR EHGGPEGMDP DGVIESNWNE IVDNFDDMNL KESLLRGIYA YGFEKPSAIQ QRAIIPCIKG YDVIAQAQSG TGKTATFAIS ILQQLEIEFK ETQALVLAPT RELAQQIQKV ILALGDYMGA TCHACIGGTN VRNEMQKLQA EAPHIVVGTP GRVFDMLNRR YLSPKWIKMF VLDEADEMLS RGFKDQIYEI FQKLNTSIQV VLLSATMPTD VLEVTKKFMR DPIRILVKKE ELTLEGIKQF YINVEREEWK LDTLCDLYET LTITQAVIFL NTRRKVDWLT EKMHARDFTV SALHGDMDQK ERDVIMREFR SGSSRVLITT DLLARGIDVQ QVSLVINYDL PTNRENYIHR IGRGGRFGRK GVAINFVTEE DKRILRDIET FYNTTVEEMP MNVADLI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Eukaryotic initiation factor 4A-II Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Eukaryotic initiation factor 4A-II Protein General Information | |
|---|---|
| Alternate Names | |
| BM-010; EIF4F; DDX2B; eIF-4A-II; EIF4A; eIF4A-II | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EIF4A2 |
| Entrez Gene ID | 1974 |
| Ensemble Gene ID | ENSG00000156976 |
| RefSeq Protein Accession(s) | NP_001958.2 |
| RefSeq mRNA Accession(s) | NM_001967.3 |
| UniProt ID(s) | Q14240 |
| UniGene ID(s) | Hs.518475 |
| HGNC ID(s) | HGNC:3284 |
| COSMIC ID Link(s) | EIF4A2 |
| KEGG Gene ID(s) | hsa:1974 |
| PharmGKB ID(s) | PA27712 |
| General Description of Recombinant Human Eukaryotic initiation factor 4A-II Protein. | |
| ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5′-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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