Human SUMO-conjugating enzyme UBC9 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant SUMO-conjugating enzyme UBC9 based upon sequence from: Human
Host: QP8322 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) SUMO-conjugating enzyme UBC9, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8322.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Pro157
Amino Acid Sequence: MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED KDWRPAITIK QILLGIQELL NEPNIQDPAQ AEAYTIYCQN RVEYEKRVRA QAKKFAP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human SUMO-conjugating enzyme UBC9 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human SUMO-conjugating enzyme UBC9 Protein General Information | |
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Alternate Names | |
P18; C358B7.1; UBC9 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | UBE2I |
Entrez Gene ID | 7329 |
Ensemble Gene ID | ENSG00000103275 |
RefSeq Protein Accession(s) | NP_003336.1 |
RefSeq mRNA Accession(s) | NM_003345.4, NM_194259.2, NM_194260.2, NM_194261.2, XM_017023640.1 |
UniProt ID(s) | P63279 |
UniGene ID(s) | Hs.302903 |
HGNC ID(s) | HGNC:12485 |
KEGG Gene ID(s) | hsa:7329 |
PharmGKB ID(s) | PA37134 |
General Description of Recombinant Human SUMO-conjugating enzyme UBC9 Protein. | |
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at ‘Lys-386’ |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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