Human Thiopurine S-methyltransferase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Thiopurine S-methyltransferase based upon sequence from: Human
Host: QP8325 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Thiopurine S-methyltransferase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8325.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Thr4 – Glu244
Amino Acid Sequence: TRTSLDIEEY SDTEVQKNQV LTLEEWQDKW VNGKTAFHQE QGHQLLKKHL DTFLKGKSGL RVFFPLCGKA VEMKWFADRG HSVVGVEISE LGIQEFFTEQ NLSYSEEPIT EIPGTKVFKS SSGNISLYCC SIFDLPRTNI GKFDMIWDRG ALVAINPGDR KCYADTMFSL LGKKFQYLLC VLSYDPTKHP GPPFYVPHAE IERLFGKICN IRCLEKVDAF EERHKSWGID CLFEKLYLLT E
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Thiopurine S-methyltransferase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human Thiopurine S-methyltransferase Protein General Information | |
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Alternate Names | |
TPMTD | |
Curated Database and Bioinformatic Data | |
Gene Symbol | TPMT |
Entrez Gene ID | 7172 |
Ensemble Gene ID | ENSG00000137364 |
RefSeq Protein Accession(s) | NP_000358.1 |
RefSeq mRNA Accession(s) | NM_000367.4, NM_001346817.1, NM_001346818.1 |
UniProt ID(s) | P51580 |
UniGene ID(s) | Hs.444319 |
HGNC ID(s) | HGNC:12014 |
COSMIC ID Link(s) | TPMT |
KEGG Gene ID(s) | hsa:7172 |
PharmGKB ID(s) | PA356 |
General Description of Recombinant Human Thiopurine S-methyltransferase Protein. | |
Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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