PDF DatasheetHuman Integrin-linked protein kinase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Integrin-linked protein kinase based upon sequence from: Human
Host: QP8343 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Integrin-linked protein kinase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8343.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Ser228
Amino Acid Sequence: MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSAVV EMLIMRGARI NVMNRGDDTP LHLAASHGHR DIVQKLLQYK ADINAVNEHG NVPLHYACFW GQDQVAEDLV ANGALVSICN KYGEMPVDKA KAPLRELLRE RAEKMGQNLN RIPYKDTFWK GTTRTRPRNG TLNKHSGIDF KQLNFLTKLN ENHSGELWKG RWQGNDIVVK VLKVRDWS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Integrin-linked protein kinase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Integrin-linked protein kinase Protein General Information | |
|---|---|
| Alternate Names | |
| HEL-S-28; p59ILK; ILK-1; ILK-2; P59 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ILK1 |
| Entrez Gene ID | 3611 |
| Ensemble Gene ID | ENSG00000166333 |
| RefSeq Protein Accession(s) | NP_001014794.1 |
| RefSeq mRNA Accession(s) | NM_001014794.2, NM_001014795.2, NM_001278441.1, NM_001278442.1, NM_004517.3, XM_005252904.4, XM_005252905.2, XM_011520065.1 |
| UniProt ID(s) | Q13418 |
| UniGene ID(s) | Hs.706355 |
| HGNC ID(s) | HGNC:6040 |
| KEGG Gene ID(s) | hsa:3611 |
| PharmGKB ID(s) | PA29855 |
| General Description of Recombinant Human Integrin-linked protein kinase Protein. | |
| Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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