PDF DatasheetHuman PSME2 / PA28b Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant PSME2 / PA28b based upon sequence from: Human
Host: QP8350 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PSME2 / PA28b, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8350.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Tyr239
Amino Acid Sequence: AKPCGVRLSG EARKQVEVFR QNLFQEAEEF LYRFLPQKII YLNQLLQEDS LNVADLTSLR APLDIPIPDP PPKDDEMETD KQEKKEVHKC GFLPGNEKVL SLLALVKPEV WTLKEKCILV ITWIQHLIPK IEDGNDFGVA IQEKVLERVN AVKTKVEAFQ TTISKYFSER GDAVAKASKE THVMDYRALV HERDEAAYGE LRAMVLDLRA FYAELYHIIS SNLEKIVNPK GEEKPSMY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human PSME2 / PA28b Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human PSME2 / PA28b Protein General Information | |
|---|---|
| Alternate Names | |
| PSME2; PA28b; REGbeta; PA28B; PA28beta | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PSME2 |
| Entrez Gene ID | 5721 |
| Ensemble Gene ID | ENSG00000100911 |
| RefSeq Protein Accession(s) | NP_002809.2 |
| RefSeq mRNA Accession(s) | NM_002818.2 |
| UniProt ID(s) | Q9UL46 |
| UniGene ID(s) | Hs.434081 |
| HGNC ID(s) | HGNC:9569 |
| COSMIC ID Link(s) | PSME2 |
| KEGG Gene ID(s) | hsa:5721 |
| PharmGKB ID(s) | PA33915 |
| General Description of Recombinant Human PSME2 / PA28b Protein. | |
| Implicated in immunoproteasome assbly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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