PDF DatasheetHuman Peroxiredoxin 1 / PRDX1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Peroxiredoxin 1 / PRDX1 based upon sequence from: Human
Host: QP8352 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Peroxiredoxin 1 / PRDX1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8352.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys199
Amino Acid Sequence: MSSGNAKIGH PAPNFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS DRAEEFKKLN CQVIGASVDS HFCHLAWVNT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITVNDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVQK SKEYFSKQK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Peroxiredoxin 1 / PRDX1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Peroxiredoxin 1 / PRDX1 Protein General Information | |
|---|---|
| Alternate Names | |
| Peroxiredoxin 1; PRDX1; Paga; OSF3; TPxA; Tdpx2; PrdxI; MSP23; OSF-3; TDX2; prx1; NkefA; PAG; PrxI | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PRDX1 |
| Entrez Gene ID | 5052 |
| Ensemble Gene ID | ENSG00000117450 |
| RefSeq Protein Accession(s) | NP_001189360.1 |
| RefSeq mRNA Accession(s) | NM_001202431.1, NM_002574.3, NM_181696.2, NM_181697.2 |
| UniProt ID(s) | Q06830 |
| UniGene ID(s) | Hs.180909 |
| HGNC ID(s) | HGNC:9352 |
| COSMIC ID Link(s) | PRDX1 |
| KEGG Gene ID(s) | hsa:5052 |
| PharmGKB ID(s) | PA33722 |
| General Description of Recombinant Human Peroxiredoxin 1 / PRDX1 Protein. | |
| Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin syst but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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