PDF DatasheetHuman Histone H2B type 1-C / E / F / G / I Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Histone H2B type 1-C / E / F / G / I based upon sequence from: Human
Host: QP8382 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histone H2B type 1-C/E/F/G/I, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8382.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Pro2 – Ser125
Amino Acid Sequence: PEPAKSAPAP KKGSKKAVTK AQKKDGKKRK RSRKESYSVY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Histone H2B type 1-C / E / F / G / I Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Histone H2B type 1-C / E / F / G / I Protein General Information | |
|---|---|
| Alternate Names | |
| H2BFB; dJ221C16.6; H2B.1B; H2B/b; HIRIP2; H2BFG; H2B/g; H2B.h; H2B/h; dJ221C16.8; H2BFH; H2B/k; H2BFK; H2B.1A; H2B/a; H2BFA; H2B.1; H2BFL; dJ221C16.3; H2B/l | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | H2BFL |
| Entrez Gene ID | 3017 |
| Ensemble Gene ID | ENSG00000180596 |
| RefSeq Protein Accession(s) | NP_003509.1 |
| RefSeq mRNA Accession(s) | NM_003518.3, NM_003522.3, NM_003523.2, NM_003525.2, NM_003526.2, NM_021063.3 |
| UniProt ID(s) | P62807 |
| UniGene ID(s) | Hs.182137 |
| HGNC ID(s) | HGNC:4757 |
| KEGG Gene ID(s) | hsa:3017 |
| PharmGKB ID(s) | PA29132 |
| General Description of Recombinant Human Histone H2B type 1-C / E / F / G / I Protein. | |
| Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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