PDF DatasheetHuman Transcription factor BTF3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Transcription factor BTF3 based upon sequence from: Human
Host: QP8384 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Transcription factor BTF3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8384.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Thr48 – Asn206
Amino Acid Sequence: TIMNQEKLAK LQAQVRIGGK GTARRKKKVV HRTATADDKK LQFSLKKLGV NNISGIEEVN MFTNQGTVIH FNNPKVQASL AANTFTITGH AETKQLTEML PSILNQLGAD SLTSLRRLAE ALPKQSVDGK APLATGEDDD DEVPDLVENF DEASKNEAN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Transcription factor BTF3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Transcription factor BTF3 Protein General Information | |
|---|---|
| Alternate Names | |
| BTF3a; BTF3b; BETA-NAC; NACB | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | BTF3 |
| Entrez Gene ID | 689 |
| Ensemble Gene ID | ENSG00000145741 |
| RefSeq Protein Accession(s) | NP_001032726.1 |
| RefSeq mRNA Accession(s) | NM_001037637.1, NM_001207.4 |
| UniProt ID(s) | P20290 |
| UniGene ID(s) | Hs.591768 |
| HGNC ID(s) | HGNC:1125 |
| COSMIC ID Link(s) | BTF3 |
| KEGG Gene ID(s) | hsa:689 |
| PharmGKB ID(s) | PA25445 |
| General Description of Recombinant Human Transcription factor BTF3 Protein. | |
| When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they erge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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