PDF DatasheetHuman Extended synaptotagmin-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Extended synaptotagmin-1 based upon sequence from: Human
Host: QP8395 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Extended synaptotagmin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8395.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Glu2 – Val245
Amino Acid Sequence: ERSPGEGPSP SPMDQPSAPS DPTDQPPAAH AKPDPGSGGQ PAGPGAAGEA LAVLTSFGRR LLVLIPVYLA GAVGLSVGFV LFGLALYLGW RRVRDEKERS LRAARQLLDD EEQLTAKTLY MSHRELPAWV SFPDVEKAEW LNKIVAQVWP FLGQYMEKLL AETVAPAVRG SNPHLQTFTF TRVELGEKPL RIIGVKVHPG QRKEQILLDL NISYVGDVQI DVEVKKYFCK AGVKGMQLHG VLRV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Extended synaptotagmin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Extended synaptotagmin-1 Protein (2-245aa) General Information | |
|---|---|
| Alternate Names | |
| FAM62A; MBC2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MBC2 |
| Entrez Gene ID | 23344 |
| Ensemble Gene ID | ENSG00000139641 |
| RefSeq Protein Accession(s) | NP_001171725.1 |
| RefSeq mRNA Accession(s) | NM_001184796.1, NM_015292.2 |
| UniProt ID(s) | Q9BSJ8 |
| UniGene ID(s) | Hs.632729 |
| HGNC ID(s) | HGNC:29534 |
| COSMIC ID Link(s) | ZNF91 |
| KEGG Gene ID(s) | hsa:23344 |
| PharmGKB ID(s) | PA165512688 |
| General Description of Recombinant Human Extended synaptotagmin-1 Protein (2-245aa). | |
| Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport . Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell mbrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell mbrane and promotes the formation of appositions between the endoplasmic reticulum and the cell mbrane. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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