PDF DatasheetHuman Small nuclear ribonucleoprotein Sm D2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Small nuclear ribonucleoprotein Sm D2 based upon sequence from: Human
Host: QP8419 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Small nuclear ribonucleoprotein Sm D2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8419.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys118
Amino Acid Sequence: MSLLNKPKSE MTPEELQKRE EEEFNTGPLS VLTQSVKNNT QVLINCRNNK KLLGRVKAFD RHCNMVLENV KEMWTEVPKS GKGKKKSKPV NKDRYISKMF LRGDSVIVVL RNPLIAGK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Small nuclear ribonucleoprotein Sm D2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Small nuclear ribonucleoprotein Sm D2 Protein General Information | |
|---|---|
| Alternate Names | |
| SMD2; SNRPD1; Sm-D2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SNRPD2 |
| Entrez Gene ID | 6633 |
| Ensemble Gene ID | ENSG00000125743 |
| RefSeq Protein Accession(s) | NP_004588.1 |
| RefSeq mRNA Accession(s) | NM_004597.6, NM_177542.3 |
| UniProt ID(s) | P62316 |
| UniGene ID(s) | Hs.515472 |
| HGNC ID(s) | HGNC:11159 |
| COSMIC ID Link(s) | SNRPD2 |
| KEGG Gene ID(s) | hsa:6633 |
| PharmGKB ID(s) | PA36000 |
| General Description of Recombinant Human Small nuclear ribonucleoprotein Sm D2 Protein. | |
| Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.