PDF DatasheetHuman U1 small nuclear ribonucleoprotein 70 kDa Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant U1 small nuclear ribonucleoprotein 70 kDa based upon sequence from: Human
Host: QP8429 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) U1 small nuclear ribonucleoprotein 70 kDa, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8429.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – His210
Amino Acid Sequence: MTQFLPPNLL ALFAPRDPIP YLPPLEKLPH EKHHNQPYCG IAPYIREFED PRDAPPPTRA ETREERMERK RREKIERRQQ EVETELKMWD PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS GKPRGYAFIE YEHERDMHSA YKHADGKKID GRRVLVDVER GRTVKGWRPR RLGGGLGGTR RGGADVNIRH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human U1 small nuclear ribonucleoprotein 70 kDa Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human U1 small nuclear ribonucleoprotein 70 kDa Protein General Information | |
|---|---|
| Alternate Names | |
| U1-70K; Snp1; U170K; SNRP70; U1AP; U1RNP; RPU1; RNPU1Z | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SNRP70 |
| Entrez Gene ID | 6625 |
| Ensemble Gene ID | ENSG00000104852 |
| RefSeq Protein Accession(s) | NP_001287998.1 |
| RefSeq mRNA Accession(s) | NM_001301069.1, NM_003089.5 |
| UniProt ID(s) | P08621 |
| UniGene ID(s) | Hs.467097 |
| HGNC ID(s) | HGNC:11150 |
| KEGG Gene ID(s) | hsa:6625 |
| PharmGKB ID(s) | PA35992 |
| General Description of Recombinant Human U1 small nuclear ribonucleoprotein 70 kDa Protein. | |
| Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5′ splice-site and the subsequent assbly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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