PDF DatasheetHuman EIF3F Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant EIF3F based upon sequence from: Human
Host: QP8436 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) EIF3F, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8436.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Phe323
Amino Acid Sequence: MATPAVPVSA PPATPTPVPA AAPASVPAPT PAPAAAPVPA AAPASSSDPA AAAAATAAPG QTPASAQAPA QTPAPALPGP ALPGPFPGGR VVRLHPVILA SIVDSYERRN EGAARVIGTL LGTVDKHSVE VTNCFSVPHN ESEDEVAVDM EFAKNMYELH KKVSPNELIL GWYATGHDIT EHSVLIHEYY SREAPNPIHL TVDTSLQNGR MSIKAYVSTL MGVPGRTMGV MFTPLTVKYA YYDTERIGVD LIMKTCFSPN RVIGLSSDLQ QVGGASARIQ DALSTVLQYA EDVLSGKVSA DNTVGRFLMS LVNQVPKIVP DDF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human EIF3F Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human EIF3F Protein General Information | |
|---|---|
| Alternate Names | |
| EIF3S5; eIF3-p47; Eukaryotic translation initiation factor 3 subunit | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EIF3F |
| Entrez Gene ID | 8665 |
| Ensemble Gene ID | ENSG00000175390 |
| RefSeq Protein Accession(s) | NP_003745.1 |
| RefSeq mRNA Accession(s) | NM_003754.2 |
| UniProt ID(s) | O00303 |
| UniGene ID(s) | Hs.516023 |
| HGNC ID(s) | HGNC:3275 |
| COSMIC ID Link(s) | EIF3F |
| KEGG Gene ID(s) | hsa:8665 |
| PharmGKB ID(s) | PA162384806 |
| General Description of Recombinant Human EIF3F Protein. | |
| Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassbly and recycling of post-termination ribosomal complexes and subsequently prevents prature joining of the 40S and 60S ribosomal subunits prior to initiation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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