PDF DatasheetHuman EIF3K Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant EIF3K based upon sequence from: Human
Host: QP8450 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) EIF3K, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8450.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Gln218
Amino Acid Sequence: AMFEQMRANV GKLLKGIDRY NPENLATLER YVETQAKENA YDLEANLAVL KLYQFNPAFF QTTVTAQILL KALTNLPHTD FTLCKCMIDQ AHQEERPIRQ ILYLGDLLET CHFQAFWQAL DENMDLLEGI TGFEDSVRKF ICHVVGITYQ HIDRWLLAEM LGDLSDSQLK VWMSKYGWSA DESGQIFICS QEESIKPKNI VEKIDFDSVS SIMASSQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human EIF3K Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human EIF3K Protein General Information | |
|---|---|
| Alternate Names | |
| EIF3K; ARG134; PRO1474; HSPC029; PLAC-24; PLAC24; EIF3S12; MSTP001; M9; EIF3-p28; PTD001 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EIF3K |
| UniProt ID(s) | Q9UBQ5 |
| COSMIC ID Link(s) | EIF3K |
| General Description of Recombinant Human EIF3K Protein. | |
| Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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