PDF DatasheetHuman Histone acetyltransferase KAT7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Histone acetyltransferase KAT7 based upon sequence from: Human
Host: QP8459 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histone acetyltransferase KAT7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8459.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Asn214
Amino Acid Sequence: MPRRKRNAGS SSDGTEDSDF STDLEHTDSS ESDGTSRRSA RVTRSSARLS QSSQDSSPVR NLQSFGTEEP AYSTRRVTRS QQQPTPVTPK KYPLRQTRSS GSETEQVVDF SDRETKNTAD HDESPPRTPT GNAPSSESDI DISSPNVSHD ESIAKDMSLK DSGSDLSHRP KRRRFHESYN FNMKCPTPGC NSLGHLTGKH ERHFSISGCP LYHN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Histone acetyltransferase KAT7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Histone acetyltransferase KAT7 Protein General Information | |
|---|---|
| Alternate Names | |
| HBO1; HBOA; MYST2; ZC2HC7 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HBO1 |
| Entrez Gene ID | 11143 |
| Ensemble Gene ID | ENSG00000136504 |
| RefSeq Protein Accession(s) | NP_001186084.1 |
| RefSeq mRNA Accession(s) | NM_001199155.1, NM_001199156.1, NM_001199157.1, NM_001199158.1, NM_007067.4 |
| UniProt ID(s) | O95251 |
| UniGene ID(s) | Hs.21907 |
| HGNC ID(s) | HGNC:17016 |
| KEGG Gene ID(s) | hsa:11143 |
| PharmGKB ID(s) | PA134886407 |
| General Description of Recombinant Human Histone acetyltransferase KAT7 Protein. | |
| Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.