PDF DatasheetHuman Heterogeneous nuclear ribonucleoprotein H Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Heterogeneous nuclear ribonucleoprotein H based upon sequence from: Human
Host: QP8472 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Heterogeneous nuclear ribonucleoprotein H, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8472.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met2 – Gly216
Amino Acid Sequence: MLGTEGGEGF VVKVRGLPWS CSADEVQRFF SDCKIQNGAQ GIRFIYTREG RPSGEAFVEL ESEDEVKLAL KKDRETMGHR YVEVFKSNNV EMDWVLKHTG PNSPDTANDG FVRLRGLPFG CSKEEIVQFF SGLEIVPNGI TLPVDFQGRS TGEAFVQFAS QEIAEKALKK HKERIGHRYI EIFKSSRAEV RTHYDPPRKL MAMQRPGPYD RPGAG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Heterogeneous nuclear ribonucleoprotein H Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Heterogeneous nuclear ribonucleoprotein H Protein (2-216aa) General Information | |
|---|---|
| Alternate Names | |
| HNRPH1; hnRNPH; HNRPH | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HNRNPH1 |
| Entrez Gene ID | 3187 |
| Ensemble Gene ID | ENSG00000169045 |
| RefSeq Protein Accession(s) | NP_001244222.1 |
| RefSeq mRNA Accession(s) | NM_001257293.1, NM_005520.2, XM_017009415.1, XM_017009416.1, XM_017009417.1 |
| UniProt ID(s) | P31943 |
| UniGene ID(s) | Hs.604001 |
| HGNC ID(s) | HGNC:5041 |
| COSMIC ID Link(s) | HNRNPH1 |
| KEGG Gene ID(s) | hsa:3187 |
| PharmGKB ID(s) | PA162391284 |
| General Description of Recombinant Human Heterogeneous nuclear ribonucleoprotein H Protein (2-216aa). | |
| This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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