PDF DatasheetHuman Tax1-binding protein 3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Tax1-binding protein 3 based upon sequence from: Human
Host: QP8476 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Tax1-binding protein 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8476.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser124
Amino Acid Sequence: MSYIPGQPVT AVVQRVEIHK LRQGENLILG FSIGGGIDQD PSQNPFSEDK TDKGIYVTRV SEGGPAEIAG LQIGDKIMQV NGWDMTMVTH DQARKRLTKR SEEVVRLLVT RQSLQKAVQQ SMLS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Tax1-binding protein 3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Tax1-binding protein 3 Protein General Information | |
|---|---|
| Alternate Names | |
| TIP1; TIP-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TAX1BP3 |
| Entrez Gene ID | 30851 |
| Ensemble Gene ID | ENSG00000213977 |
| RefSeq Protein Accession(s) | NP_001191627.1 |
| RefSeq mRNA Accession(s) | NM_001204698.1, NM_014604.3 |
| UniProt ID(s) | O14907 |
| UniGene ID(s) | Hs.12956 |
| HGNC ID(s) | HGNC:30684 |
| COSMIC ID Link(s) | TAX1BP3 |
| KEGG Gene ID(s) | hsa:30851 |
| PharmGKB ID(s) | PA134950693 |
| General Description of Recombinant Human Tax1-binding protein 3 Protein. | |
| May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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