PDF DatasheetHuman GP25L2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GP25L2 based upon sequence from: Human
Host: QP8481 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GP25L2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8481.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Phe40 – Glu197
Amino Acid Sequence: FHIGETEKKC FIEEIPDETM VIGNYRTQLY DKQREEYQPA TPGLGMFVEV KDPEDKVILA RQYGSEGRFT FTSHTPGEHQ ICLHSNSTKF SLFAGGMLRV HLDIQVGEHA NDYAEIAAKD KLSELQLRVR QLVEQVEQIQ KEQNYQRWRE ERFRQTSE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GP25L2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human GP25L2 Protein General Information | |
|---|---|
| Alternate Names | |
| GMP25; HSGP25L2G; p24a2; p25; p24alpha2; Transmembrane emp24 domain-containing protein | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GP25L2 |
| Entrez Gene ID | 54732 |
| Ensemble Gene ID | ENSG00000184840 |
| RefSeq Protein Accession(s) | NP_059980.2 |
| RefSeq mRNA Accession(s) | NM_017510.5 |
| UniProt ID(s) | Q9BVK6 |
| UniGene ID(s) | Hs.279929 |
| HGNC ID(s) | HGNC:24878 |
| KEGG Gene ID(s) | hsa:54732 |
| PharmGKB ID(s) | PA134881976 |
| General Description of Recombinant Human GP25L2 Protein. | |
| Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to mbranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi mbranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular mbranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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