PDF DatasheetHuman Dr1-associated corepressor Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Dr1-associated corepressor based upon sequence from: Human
Host: QP8494 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Dr1-associated corepressor, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8494.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Lys4 – Glu198
Amino Acid Sequence: KKKKYNARFP PARIKKIMQT DEEIGKVAAA VPVIISRALE LFLESLLKKA CQVTQSRNAK TMTTSHLKQC IELEQQFDFL KDLVASVPDM QGDGEDNHMD GDKGARRGRK PGSGGRKNGG MGTKSKDKKL SGTDSEQEDE SEDTDTDGEE ETSQPPPQAS HPSAHFQSPP TPFLPFASTL PLPPAPPGPS APDEE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Dr1-associated corepressor Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Dr1-associated corepressor Protein General Information | |
|---|---|
| Alternate Names | |
| NC2-alpha | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DRAP1 |
| Entrez Gene ID | 10589 |
| Ensemble Gene ID | ENSG00000175550 |
| RefSeq Protein Accession(s) | NP_006433.2 |
| RefSeq mRNA Accession(s) | NM_006442.3 |
| UniProt ID(s) | Q14919 |
| UniGene ID(s) | Hs.356742 |
| HGNC ID(s) | HGNC:3019 |
| COSMIC ID Link(s) | DRAP1 |
| KEGG Gene ID(s) | hsa:10589 |
| PharmGKB ID(s) | PA27476 |
| General Description of Recombinant Human Dr1-associated corepressor Protein. | |
| The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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