PDF DatasheetHuman GABARAP / Apg8p1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GABARAP / Apg8p1 based upon sequence from: Human
Host: QP8508 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GABARAP / Apg8p1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8508.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Lys2 – Leu117
Amino Acid Sequence: KFVYKEEHPF EKRRSEGEKI RKKYPDRVPV IVEKAPKARI GDLDKKKYLV PSDLTVGQFY FLIRKRIHLR AEDALFFFVN NVIPPTSATM GQLYQEHHEE DFFLYIAYSD ESVYGL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GABARAP / Apg8p1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human GABARAP / Apg8p1 Protein General Information | |
|---|---|
| Alternate Names | |
| GABARAP; Apg8p1; GABARAP-a; ATG8A; MM46 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GABARAP |
| Entrez Gene ID | 11337 |
| Ensemble Gene ID | ENSG00000170296 |
| RefSeq Protein Accession(s) | NP_009209.1 |
| RefSeq mRNA Accession(s) | NM_007278.1 |
| UniProt ID(s) | O95166 |
| UniGene ID(s) | Hs.647421 |
| HGNC ID(s) | HGNC:4067 |
| COSMIC ID Link(s) | GABARAP |
| KEGG Gene ID(s) | hsa:11337 |
| PharmGKB ID(s) | PA28480 |
| General Description of Recombinant Human GABARAP / Apg8p1 Protein. | |
| Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore mbrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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