PDF DatasheetHuman Tissue factor pathway inhibitor Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Tissue factor pathway inhibitor based upon sequence from: Human
Host: QP8567 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Tissue factor pathway inhibitor, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8567.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asp29 – Leu280
Amino Acid Sequence: DSEEDEEHTI ITDTELPPLK LMHSFCAFKA DDGPCKAIMK RFFFNIFTRQ CEEFIYGGCE GNQNRFESLE ECKKMCTRDN ANRIIKTTLQ QEKPDFCFLE EDPGICRGYI TRYFYNNQTK QCERFKYGGC LGNMNNFETL EECKNICEDG PNGFQVDNYG TQLNAVNNSL TPQSTKVPSL FEFHGPSWCL TPADRGLCRA NENRFYYNSV IGKCRPFKYS GCGGNENNFT SKQECLRACK KGFIQRISKG GL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Tissue factor pathway inhibitor Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Tissue factor pathway inhibitor Protein General Information | |
|---|---|
| Alternate Names | |
| LACI; EPI; TFI; TFPI1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LACI |
| Entrez Gene ID | 7035 |
| Ensemble Gene ID | ENSG00000003436 |
| RefSeq Protein Accession(s) | NP_001027452.1 |
| RefSeq mRNA Accession(s) | NM_001032281.3, NM_001318941.2, NM_001329239.1, NM_001329240.1, NM_001329241.1, NM_006287.5, XM_005246819.1, XM_006712720.3, XM_011511709.2 |
| UniProt ID(s) | P10646 |
| UniGene ID(s) | Hs.516578 |
| HGNC ID(s) | HGNC:11760 |
| KEGG Gene ID(s) | hsa:7035 |
| PharmGKB ID(s) | PA36475 |
| General Description of Recombinant Human Tissue factor pathway inhibitor Protein. | |
| Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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