Human Thrombospondin-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Thrombospondin-1 based upon sequence from: Human
Host: QP8570 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Thrombospondin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8570.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asn19 – Lys350
Amino Acid Sequence: NRIPESGGDN SVFDIFELTG AARKGSGRRL VKGPDPSSPA FRIEDANLIP PVPDDKFQDL VDAVRAEKGF LLLASLRQMK KTRGTLLALE RKDHSGQVFS VVSNGKAGTL DLSLTVQGKQ HVVSVEEALL ATGQWKSITL FVQEDRAQLY IDCEKMENAE LDVPIQSVFT RDLASIARLR IAKGGVNDNF QGVLQNVRFV FGTTPEDILR NKGCSSSTSV LLTLDNNVVN GSSPAIRTNY IGHKTKDLQA ICGISCDELS SMVLELRGLR TIVTTLQDSI RKVTEENKEL ANELRRPPLC YHNGVQYRNN EEWTVDSCTE CHCQNSVTIC KK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Thrombospondin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human Thrombospondin-1 Protein General Information | |
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Alternate Names | |
TSP; TSP1; THBS; THBS-1; TSP-1 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | THBS1 |
Entrez Gene ID | 7057 |
Ensemble Gene ID | ENSG00000137801 |
RefSeq Protein Accession(s) | NP_003237.2 |
RefSeq mRNA Accession(s) | NM_003246.3 |
UniProt ID(s) | P07996 |
UniGene ID(s) | Hs.164226 |
HGNC ID(s) | HGNC:11785 |
COSMIC ID Link(s) | THBS1 |
KEGG Gene ID(s) | hsa:7057 |
PharmGKB ID(s) | PA36497 |
General Description of Recombinant Human Thrombospondin-1 Protein. | |
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp . Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors . |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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