PDF DatasheetHuman CALR / Calreticulin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CALR / Calreticulin based upon sequence from: Human
Host: QP8591 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CALR / Calreticulin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8591.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu18 – Leu417
Amino Acid Sequence: EPAVYFKEQF LDGDGWTSRW IESKHKSDFG KFVLSSGKFY GDEEKDKGLQ TSQDARFYAL SASFEPFSNK GQTLVVQFTV KHEQNIDCGG GYVKLFPNSL DQTDMHGDSE YNIMFGPDIC GPGTKKVHVI FNYKGKNVLI NKDIRCKDDE FTHLYTLIVR PDNTYEVKID NSQVESGSLE DDWDFLPPKK IKDPDASKPE DWDERAKIDD PTDSKPEDWD KPEHIPDPDA KKPEDWDEEM DGEWEPPVIQ NPEYKGEWKP RQIDNPDYKG TWIHPEIDNP EYSPDPSIYA YDNFGVLGLD LWQVKSGTIF DNFLITNDEA YAEEFGNETW GVTKAAEKQM KDKQDEEQRL KEEEEDKKRK EEEEAEDKED DEDKDEDEED EEDKEEDEEE DVPGQAKDEL
Purity: Greater than 85.1% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CALR / Calreticulin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CALR / Calreticulin Protein General Information | |
|---|---|
| Alternate Names | |
| CALR; Calreticulin; HEL-S-99n; CRT; SSA; cC1qR; RO | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CALR |
| Entrez Gene ID | 811 |
| Ensemble Gene ID | ENSG00000179218 |
| RefSeq Protein Accession(s) | NP_004334.1 |
| RefSeq mRNA Accession(s) | NM_004343.3 |
| UniProt ID(s) | P27797 |
| UniGene ID(s) | Hs.515162 |
| HGNC ID(s) | HGNC:1455 |
| COSMIC ID Link(s) | CALR |
| KEGG Gene ID(s) | hsa:811 |
| PharmGKB ID(s) | PA26046 |
| General Description of Recombinant Human CALR / Calreticulin Protein. | |
| Calcium-binding chaperone that promotes folding, oligomeric assbly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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