PDF DatasheetMouse Adiponectin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Adiponectin based upon sequence from: Mouse
Host: QP8593 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Adiponectin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8593.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu18 – Asn247
Amino Acid Sequence: EDDVTTTEEL APALVPPPKG TCAGWMAGIP GHPGHNGTPG RDGRDGTPGE KGEKGDAGLL GPKGETGDVG MTGAEGPRGF PGTPGRKGEP GEAAYVYRSA FSVGLETRVT VPNVPIRFTK IFYNQQNHYD GSTGKFYCNI PGLYYFSYHI TVYMKDVKVS LFKKDKAVLF TYDQYQEKNV DQASGSVLLH LEVGDQVWLQ VYGDGDHNGL YADNVNDSTF TGFLLYHDTN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse Adiponectin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Adiponectin Protein General Information | |
|---|---|
| Alternate Names | |
| GBP28; adipo; Acdc; APN; Ad; 30kDa; Acrp30; apM1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ma/Adipoq |
| Entrez Gene ID | 11450 |
| Ensemble Gene ID | ENSMUSG00000022878 |
| RefSeq Protein Accession(s) | NP_033735.3 |
| RefSeq mRNA Accession(s) | NM_009605.5 |
| UniProt ID(s) | Q60994 |
| UniGene ID(s) | Mm.3969 |
| KEGG Gene ID(s) | mmu:11450 |
| General Description of Recombinant Mouse Adiponectin Protein. | |
| Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue rodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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