Human Substance-P receptor Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Substance-P receptor based upon sequence from: Human
Host: QP8669 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Substance-P receptor, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8669.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Met1 – Ala29
Amino Acid Sequence: MDNVLPVDSD LSPNISTNTS EPNQFVQPA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Substance-P receptor Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human Substance-P receptor Protein General Information | |
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Alternate Names | |
TAC1R; NK1R; NKIR; SPR | |
Curated Database and Bioinformatic Data | |
Gene Symbol | NK1R |
Entrez Gene ID | 6869 |
Ensemble Gene ID | ENSG00000115353 |
RefSeq Protein Accession(s) | NP_001049.1 |
RefSeq mRNA Accession(s) | NM_001058.3, NM_015727.2 |
UniProt ID(s) | P25103 |
UniGene ID(s) | Hs.633301 |
HGNC ID(s) | HGNC:11526 |
KEGG Gene ID(s) | hsa:6869 |
PharmGKB ID(s) | PA36302 |
General Description of Recombinant Human Substance-P receptor Protein. | |
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger syst. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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