PDF DatasheetHuman SerpinE1 / PAI-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant SerpinE1 / PAI-1 based upon sequence from: Human
Host: QP8711 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) SerpinE1 / PAI-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8711.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Val24 – Glu401
Amino Acid Sequence: VHHPPSYVAH LASDFGVRVF QQVAQASKDR NVVFSPYGVA SVLAMLQLTT GGETQQQIQA AMGFKIDDKG MAPALRHLYK ELMGPWNKDE ISTTDAIFVQ RDLKLVQGFM PHFFRLFRST VKQVDFSEVE RARFIINDWV KTHTKGMISN LLGKGAVDQL TRLVLVNALY FNGQWKTPFP DSSTHRRLFH KSDGSTVSVP MMAQTNKFNY TEFTTPDGHY YDILELPYHG DTLSMFIAAP YEKEVPLSAL TNILSAQLIS HWKGNMTRLP RLLVLPKFSL ETEVDLRKPL ENLGMTDMFR QFQADFTSLS DQEPLHVAQA LQKVKIEVNE SGTVASSSTA VIVSARMAPE EIIMDRPFLF VVRHNPTGTV LFMGQVME
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human SerpinE1 / PAI-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human SerpinE1 / PAI-1 Protein General Information | |
|---|---|
| Alternate Names | |
| SerpinE1; PAI-1; Planh; Pai1aa; PAI1A; Pai1; RATPAI1A | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SERPINE1 |
| Entrez Gene ID | 5054 |
| Ensemble Gene ID | ENSG00000106366 |
| RefSeq Protein Accession(s) | NP_000593.1 |
| RefSeq mRNA Accession(s) | NM_000602.4 |
| UniProt ID(s) | P05121 |
| UniGene ID(s) | Hs.414795 |
| HGNC ID(s) | HGNC:8583 |
| COSMIC ID Link(s) | SERPINE1 |
| KEGG Gene ID(s) | hsa:5054 |
| PharmGKB ID(s) | PA261 |
| General Description of Recombinant Human SerpinE1 / PAI-1 Protein. | |
| Serine protease inhibitor. This inhibitor acts as ‘bait’ for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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