PDF DatasheetHuman 14-3-3 sigma / Stratifin / YWHAS Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant 14-3-3 sigma / Stratifin / YWHAS based upon sequence from: Human
Host: QP872 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) 14-3-3 sigma / Stratifin / YWHAS, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP872.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser248
Amino Acid Sequence: MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG EAPQEPQS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human 14-3-3 sigma / Stratifin / YWHAS Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human 14-3-3 sigma / Stratifin / YWHAS Protein General Information | |
|---|---|
| Alternate Names | |
| 14-3-3 sigma, Stratifin, YWHAS, Er, Ywhas, Mme1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SFN |
| Entrez Gene ID | 2810 |
| Ensemble Gene ID | ENSG00000175793 |
| RefSeq Protein Accession(s) | NP_006133.1 |
| RefSeq mRNA Accession(s) | NM_006142.3 |
| UniProt ID(s) | P31947 |
| UniGene ID(s) | Hs.523718 |
| HGNC ID(s) | HGNC:10773 |
| COSMIC ID Link(s) | SFN |
| KEGG Gene ID(s) | hsa:2810 |
| PharmGKB ID(s) | PA177 |
| General Description of Recombinant Human 14-3-3 sigma / Stratifin / YWHAS Protein. | |
| Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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