Human Multidrug resistance protein 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Multidrug resistance protein 1 based upon sequence from: Human
Host: QP8727 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Multidrug resistance protein 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8727.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Leu236 – Ile297
Amino Acid Sequence: LSSFTDKELL AYAKAGAVAE EVLAAIRTVI AFGGQKKELE RYNKNLEEAK RIGIKKAITA NI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Multidrug resistance protein 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human Multidrug resistance protein 1 Protein General Information | |
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Alternate Names | |
GP170; ABC20; CD243; MDR1; P-GP; CLCS; PGY1 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | ABCB1 |
Entrez Gene ID | 5243 |
Ensemble Gene ID | ENSG00000085563 |
RefSeq Protein Accession(s) | NP_000918.2 |
RefSeq mRNA Accession(s) | NM_000927.4 |
UniProt ID(s) | P08183 |
UniGene ID(s) | Hs.489033 |
HGNC ID(s) | HGNC:40 |
COSMIC ID Link(s) | ABCB1 |
KEGG Gene ID(s) | hsa:5243 |
PharmGKB ID(s) | PA267 |
General Description of Recombinant Human Multidrug resistance protein 1 Protein. | |
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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