PDF DatasheetHuman Collagen alpha-1(XVIII) chain Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Collagen alpha-1(XVIII) chain based upon sequence from: Human
Host: QP8749 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Collagen alpha-1(XVIII) chain, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8749.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gln1578 – Lys1754
Amino Acid Sequence: QPVLHLVALN SPLSGGMRGI RGADFQCFQQ ARAVGLAGTF RAFLSSRLQD LYSIVRRADR AAVPIVNLKD ELLFPSWEAL FSGSEGPLKP GARIFSFDGK DVLRHPTWPQ KSVWHGSDPN GRRLTESYCE TWRTEAPSAT GQASSLLGGR LLGQSAASCH HAYIVLCIEN SFMTASK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Collagen alpha-1(XVIII) chain Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Collagen alpha-1(XVIII) chain Protein General Information | |
|---|---|
| Alternate Names | |
| KNO; KNO1; KS | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | COL18A1 |
| Entrez Gene ID | 80781 |
| Ensemble Gene ID | ENSG00000182871 |
| RefSeq Protein Accession(s) | NP_085059.2 |
| RefSeq mRNA Accession(s) | NM_030582.3, NM_130444.2, NM_130445.3 |
| UniProt ID(s) | P39060 |
| UniGene ID(s) | Hs.517356 |
| HGNC ID(s) | HGNC:2195 |
| COSMIC ID Link(s) | COL18A1 |
| KEGG Gene ID(s) | hsa:80781 |
| PharmGKB ID(s) | PA26711 |
| General Description of Recombinant Human Collagen alpha-1(XVIII) chain Protein. | |
| COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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