PDF DatasheetHuman Tropomyosin beta chain Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Tropomyosin beta chain based upon sequence from: Human
Host: QP8763 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Tropomyosin beta chain, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8763.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asp14 – Leu284
Amino Acid Sequence: DKENAIDRAE QAEADKKQAE DRCKQLEEEQ QALQKKLKGT EDEVEKYSES VKEAQEKLEQ AEKKATDAEA DVASLNRRIQ LVEEELDRAQ ERLATALQKL EEAEKAADES ERGMKVIENR AMKDEEKMEL QEMQLKEAKH IAEDSDRKYE EVARKLVILE GELERSEERA EVAESKCGDL EEELKIVTNN LKSLEAQADK YSTKEDKYEE EIKLLEEKLK EAETRAEFAE RSVAKLEKTI DDLEDEVYAQ KMKYKAISEE LDNALNDITS L
Purity: Greater than 86.7% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Tropomyosin beta chain Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Tropomyosin beta chain Protein General Information | |
|---|---|
| Alternate Names | |
| DA2B; NEM4; AMCD1; HEL-S-273; DA1; TMSB | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TMSB |
| Entrez Gene ID | 7169 |
| Ensemble Gene ID | ENSG00000198467 |
| RefSeq Protein Accession(s) | NP_003280.2 |
| RefSeq mRNA Accession(s) | NM_003289.3, NM_213674.1, XM_017015091.1 |
| UniProt ID(s) | P07951 |
| UniGene ID(s) | Hs.300772 |
| HGNC ID(s) | HGNC:12011 |
| KEGG Gene ID(s) | hsa:7169 |
| PharmGKB ID(s) | PA36691 |
| General Description of Recombinant Human Tropomyosin beta chain Protein. | |
| Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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