PDF DatasheetHuman Plexin-A1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Plexin-A1 based upon sequence from: Human
Host: QP8791 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Plexin-A1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8791.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Leu986 – Leu1152
Amino Acid Sequence: LNAGSDVAVS VGGRPCSFSW RNSREIRCLT PPGQSPGSAP IIININRAQL TNPEVKYNYT EDPTILRIDP EWSINSGGTL LTVTGTNLAT VREPRIRAKY GGIERENGCL VYNDTTMVCR APSVANPVRS PPELGERPDE LGFVMDNVRS LLVLNSTSFL YYPDPVL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Plexin-A1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Plexin-A1 Protein General Information | |
|---|---|
| Alternate Names | |
| PLEXIN-A1; PLXN1; NOV; NOVP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PLXNA1 |
| Entrez Gene ID | 5361 |
| Ensemble Gene ID | ENSG00000114554 |
| RefSeq Protein Accession(s) | NP_115618.3 |
| RefSeq mRNA Accession(s) | NM_032242.3 |
| UniProt ID(s) | Q9UIW2 |
| UniGene ID(s) | Hs.432329 |
| HGNC ID(s) | HGNC:9099 |
| COSMIC ID Link(s) | PLXNA1 |
| KEGG Gene ID(s) | hsa:5361 |
| General Description of Recombinant Human Plexin-A1 Protein. | |
| Coreceptor for SA3A, SA3C, SA3F and SA6D. Necessary for signaling by class 3 saphorins and subsequent rodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 saphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific saphorins, and its Cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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