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Human Ceruloplasmin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ceruloplasmin based upon sequence from: Human
Host: QP8808 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ceruloplasmin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8808.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ile807 – Met1050
Amino Acid Sequence: ILGPQLHADV GDKVKIIFKN MATRPYSIHA HGVQTESSTV TPTLPGETLT YVWKIPERSG AGTEDSACIP WAYYSTVDQV KDLYSGLIGP LIVCRRPYLK VFNPRRKLEF ALLFLVFDEN ESWYLDDNIK TYSDHPEKVN KDDEEFIESN KMHAINGRMF GNLQGLTMHV GDEVNWYLMG MGNEIDLHTV HFHGHSFQYK HRGVYSSDVF DIFPGTYQTL EMFPRTPGIW LLHCHVTDHI HAGM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Ceruloplasmin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Ceruloplasmin Protein General Information | |
|---|---|
| Alternate Names | |
| CP-2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CP |
| Entrez Gene ID | 1356 |
| Ensemble Gene ID | ENSG00000047457 |
| RefSeq Protein Accession(s) | NP_000087.1 |
| RefSeq mRNA Accession(s) | NM_000096.3 |
| UniProt ID(s) | P00450 |
| UniGene ID(s) | Hs.558314 |
| HGNC ID(s) | HGNC:2295 |
| COSMIC ID Link(s) | CP |
| KEGG Gene ID(s) | hsa:1356 |
| PharmGKB ID(s) | PA26815 |
| General Description of Recombinant Human Ceruloplasmin Protein. | |
| Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe2+ to Fe3+ without releasing radical oxygen species. It is involved in iron transport across the cell mbrane. Provides Cu2+ ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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