PDF DatasheetBovine Angiogenin-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Angiogenin-1 based upon sequence from: Bovine
Host: QP8810 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Bos taurus (Bovine) Angiogenin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8810.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala24 – His148
Amino Acid Sequence: AQDDYRYIHF LTQHYDAKPK GRNDEYCFNM MKNRRLTRPC KDRNTFIHGN KNDIKAICED RNGQPYRGDL RISKSEFQIT ICKHKGGSSR PPCRYGATED SRVIVVGCEN GLPVHFDESF ITPRH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Bovine Angiogenin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Bovine Angiogenin-1 Protein General Information | |
|---|---|
| Alternate Names | |
| ANG1; RAA1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ANG1 |
| UniProt ID(s) | P10152 |
| UniGene ID(s) | Bt.12722 |
| General Description of Recombinant Bovine Angiogenin-1 Protein. | |
| Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assbly of stress granules (SGs) . Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. Has very low ribonuclease activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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