PDF DatasheetHuman CASP7 / caspase 7 / MCH3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CASP7 / caspase 7 / MCH3 based upon sequence from: Human
Host: QP8834 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CASP7 / caspase 7 / MCH3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8834.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala207 – Gln303
Amino Acid Sequence: ANPRYKIPVE ADFLFAYSTV PGYYSWRSPG RGSWFVQALC SILEEHGKDL EIMQILTRVN DRVARHFESQ SDDPHFHEKK QIPCVVSMLT KELYFSQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CASP7 / caspase 7 / MCH3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CASP7 / caspase 7 / MCH3 Protein (207-303aa) General Information | |
|---|---|
| Alternate Names | |
| CASP7; caspase 7; MCH3; ICE-LAP3; CMH-1; CASP-7; MCH3; LICE2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CASP7 |
| Entrez Gene ID | 840 |
| Ensemble Gene ID | ENSG00000165806 |
| RefSeq Protein Accession(s) | NP_001218.1 |
| RefSeq mRNA Accession(s) | NM_001227.4, NM_001267056.1, NM_001267057.1, NM_001267058.1, NM_001320911.1, NM_033338.5, NM_033339.4, NM_033340.3 |
| UniProt ID(s) | P55210 |
| UniGene ID(s) | Hs.9216 |
| HGNC ID(s) | HGNC:1508 |
| COSMIC ID Link(s) | CASP7 |
| KEGG Gene ID(s) | hsa:840 |
| PharmGKB ID(s) | PA26091 |
| General Description of Recombinant Human CASP7 / caspase 7 / MCH3 Protein (207-303aa). | |
| Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory elent binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ‘216-Asp-|-Gly-217’ bond. Overexpression promotes programmed cell death. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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