PDF DatasheetHuman Replication protein A 30 kDa subunit Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Replication protein A 30 kDa subunit based upon sequence from: Human
Host: QP8854 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Replication protein A 30 kDa subunit, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8854.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Ala260
Amino Acid Sequence: MSKSGFGSYG SISAADGASG GSDQLCERDA TPAIKTQRPK VRIQDVVPCN VNQLLSSTVF DPVFKVRGII VSQVSIVGVI RGAEKASNHI CYKIDDMTAK PIEARQWFGR EKVKQVTPLS VGVYVKVFGI LKCPTGTKSL EVLKIHVLED MNEFTVHILE TVNAHMMLDK ARRDTTVESV PVSPSEVNDA GDNDESHRNF IQDEVLRLIH ECPHQEGKSI HELRAQLCDL SVKAIKEAID YLTVEGHIYP TVDREHFKSA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Replication protein A 30 kDa subunit Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Replication protein A 30 kDa subunit Protein General Information | |
|---|---|
| Alternate Names | |
| HSU24186 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RPA4 |
| Entrez Gene ID | 29935 |
| Ensemble Gene ID | ENSG00000204086 |
| RefSeq Protein Accession(s) | NP_037479.1 |
| RefSeq mRNA Accession(s) | NM_013347.4 |
| UniProt ID(s) | Q13156 |
| UniGene ID(s) | Hs.659349 |
| HGNC ID(s) | HGNC:30305 |
| COSMIC ID Link(s) | RPA4 |
| KEGG Gene ID(s) | hsa:29935 |
| PharmGKB ID(s) | PA134988548 |
| General Description of Recombinant Human Replication protein A 30 kDa subunit Protein. | |
| As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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