PDF DatasheetHuman Transcription factor PU.1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Transcription factor PU.1 based upon sequence from: Human
Host: QP8867 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Transcription factor PU.1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8867.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – His270
Amino Acid Sequence: MLQACKMEGF PLVPPPSEDL VPYDTDLYQR QTHEYYPYLS SDGESHSDHY WDFHPHHVHS EFESFAENNF TELQSVQPPQ LQQLYRHMEL EQMHVLDTPM VPPHPSLGHQ VSYLPRMCLQ YPSLSPAQPS SDEEEGERQS PPLEVSDGEA DGLEPGPGLL PGETGSKKKI RLYQFLLDLL RSGDMKDSIW WVDKDKGTFQ FSSKHKEALA HRWGIQKGNR KKMTYQKMAR ALRNYGKTGE VKKVKKKLTY QFSGEVLGRG GLAERRHPPH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Transcription factor PU.1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Transcription factor PU.1 Protein General Information | |
|---|---|
| Alternate Names | |
| OF; PU.1; SPI-A; SFPI1; SPI-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SPI1 |
| Entrez Gene ID | 6688 |
| Ensemble Gene ID | ENSG00000066336 |
| RefSeq Protein Accession(s) | NP_001074016.1 |
| RefSeq mRNA Accession(s) | NM_001080547.1, NM_003120.2 |
| UniProt ID(s) | P17947 |
| UniGene ID(s) | Hs.502511 |
| HGNC ID(s) | HGNC:11241 |
| COSMIC ID Link(s) | SPI1 |
| KEGG Gene ID(s) | hsa:6688 |
| PharmGKB ID(s) | PA36071 |
| General Description of Recombinant Human Transcription factor PU.1 Protein. | |
| Binds to the PU-box, a purine-rich DNA sequence (5′-GAGGAA-3′) that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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