PDF DatasheetHuman Telomerase protein component 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Telomerase protein component 1 based upon sequence from: Human
Host: QP8918 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Telomerase protein component 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8918.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Leu2392 – Glu2594
Amino Acid Sequence: LKLLCMKPGD APSEIWSSYT ENPMILSTHK EYGIFVLQPK DPGVLSFLRQ KESGEFEERL NFDINLENPS RTLISITQAK PESESSFLCA SSDGILWNLA KCSPEGEWTT GNMWQKKANT PETQTPGTDP STCRESDASM DSDASMDSEP TPHLKTRQRR KIHSGSVTAL HVLPELLVTA SKDRDVKLWE RPSMQLLGLF RCE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Telomerase protein component 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Telomerase protein component 1 Protein (2392-2594aa) General Information | |
|---|---|
| Alternate Names | |
| TROVE1; p240; VAULT2; TP1; TLP1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TEP1 |
| Entrez Gene ID | 7011 |
| Ensemble Gene ID | ENSG00000129566 |
| RefSeq Protein Accession(s) | NP_009041.2 |
| RefSeq mRNA Accession(s) | NM_007110.4, XM_005268027.4 |
| UniProt ID(s) | Q99973 |
| UniGene ID(s) | Hs.508835 |
| HGNC ID(s) | HGNC:11726 |
| COSMIC ID Link(s) | TEP1 |
| KEGG Gene ID(s) | hsa:7011 |
| PharmGKB ID(s) | PA36443 |
| General Description of Recombinant Human Telomerase protein component 1 Protein (2392-2594aa). | |
| Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-Cytoplasmic domain transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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