PDF DatasheetHuman Collagen alpha-1(XVII) chain Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Collagen alpha-1(XVII) chain based upon sequence from: Human
Host: QP8920 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Collagen alpha-1(XVII) chain, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8920.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Tyr1253 – Pro1497
Amino Acid Sequence: YLTSPDVRSF IVGPPGPPGP QGPPGDSRLL STDASHSRGS SSSSHSSSVR RGSSYSSSMS TGGGGAGSLG AGGAFGEAAG DRGPYGTDIG PGGGYGAAAE GGMYAGNGGL LGADFAGDLD YNELAVRVSE SMQRQGLLQG MAYTVQGPPG QPGPQGPPGI SKVFSAYSNV TADLMDFFQT YGAIQGPPGQ KGEMGTPGPK GDRGPAGPPG HPGPPGPRGH KGEKGDKGDQ VYAGRRRRRS IAVKP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Collagen alpha-1(XVII) chain Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Collagen alpha-1(XVII) chain Protein General Information | |
|---|---|
| Alternate Names | |
| BPA-2; BPAG2; BA16H23.2; BP180; LAD-1; ERED | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | COL17A1 |
| Entrez Gene ID | 1308 |
| Ensemble Gene ID | ENSG00000065618 |
| RefSeq Protein Accession(s) | NP_000485.3 |
| RefSeq mRNA Accession(s) | NM_000494.3 |
| UniProt ID(s) | Q9UMD9 |
| UniGene ID(s) | Hs.117938 |
| HGNC ID(s) | HGNC:2194 |
| COSMIC ID Link(s) | COL17A1 |
| KEGG Gene ID(s) | hsa:1308 |
| PharmGKB ID(s) | PA26710 |
| General Description of Recombinant Human Collagen alpha-1(XVII) chain Protein. | |
| May play a role in the integrity of hidesmosome and the attachment of basal keratinocytes to the underlying basent mbrane.The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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