PDF DatasheetHuman Beta-1 adrenergic receptor Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Beta-1 adrenergic receptor based upon sequence from: Human
Host: QP8958 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Beta-1 adrenergic receptor, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8958.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Cys378 – Val477
Amino Acid Sequence: CRSPDFRKAF QRLLCCARRA ARRRHATHGD RPRASGCLAR PGPPPSPGAA SDDDDDDVVG ATPPARLLEP WAGCNGGAAA DSDSSLDEPC RPGFASESKV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Beta-1 adrenergic receptor Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Beta-1 adrenergic receptor Protein General Information | |
|---|---|
| Alternate Names | |
| B1AR; ADRB1R; BETA1AR; RHR | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ADRB1 |
| Entrez Gene ID | 153 |
| Ensemble Gene ID | ENSG00000043591 |
| RefSeq Protein Accession(s) | NP_000675.1 |
| RefSeq mRNA Accession(s) | NM_000684.2 |
| UniProt ID(s) | P08588 |
| UniGene ID(s) | Hs.99913 |
| HGNC ID(s) | HGNC:285 |
| COSMIC ID Link(s) | ADRB1 |
| KEGG Gene ID(s) | hsa:153 |
| PharmGKB ID(s) | PA38 |
| General Description of Recombinant Human Beta-1 adrenergic receptor Protein. | |
| Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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