PDF DatasheetHuman Apoptotic protease-activating factor 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Apoptotic protease-activating factor 1 based upon sequence from: Human
Host: QP8984 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Apoptotic protease-activating factor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8984.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser104 – Leu415
Amino Acid Sequence: SGITSYVRTV LCEGGVPQRP VVFVTRKKLV NAIQQKLSKL KGEPGWVTIH GMAGCGKSVL AAEAVRDHSL LEGCFPGGVH WVSVGKQDKS GLLMKLQNLC TRLDQDESFS QRLPLNIEEA KDRLRILMLR KHPRSLLILD DVWDSWVLKA FDSQCQILLT TRDKSVTDSV MGPKYVVPVE SSLGKEKGLE ILSLFVNMKK ADLPEQAHSI IKECKGSPLV VSLIGALLRD FPNRWEYYLK QLQNKQFKRI RKSSSYDYEA LDEAMSISVE MLREDIKDYY TDLSILQKDV KVPTKVLCIL WDMETEEVED IL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Apoptotic protease-activating factor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Apoptotic protease-activating factor 1 Protein General Information | |
|---|---|
| Alternate Names | |
| APAF-1; CED4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | APAF1 |
| Entrez Gene ID | 317 |
| Ensemble Gene ID | ENSG00000120868 |
| RefSeq Protein Accession(s) | NP_001151.1 |
| RefSeq mRNA Accession(s) | NM_001160.2, NM_013229.2, NM_181861.1, NM_181868.1, NM_181869.1 |
| UniProt ID(s) | O14727 |
| UniGene ID(s) | Hs.552567 |
| HGNC ID(s) | HGNC:576 |
| COSMIC ID Link(s) | APAF1 |
| KEGG Gene ID(s) | hsa:317 |
| PharmGKB ID(s) | PA24868 |
| General Description of Recombinant Human Apoptotic protease-activating factor 1 Protein. | |
| Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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